Patient Guide: A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Why Use Quri.ai for This Trial?

  • ✓ Simplified eligibility checker - know if you qualify in minutes
  • ✓ Direct contact with study coordinators at 12 locations
  • ✓ Plain language explanations of medical terms and procedures
  • ✓ Personalized enrollment support throughout your journey
  • ✓ Free service - no hidden fees or obligations
Trial ID: NCTNCT06439082
Status: 🟢 Enrolling Now
Condition: Sickle Cell Disease
Phase: PHASE3

Where You Can Participate

This study is available at 12 locations across the country.

Top locations include:
  • • Washington D.C., District of Columbia
  • • Jacksonville, Florida
  • • Augusta, Georgia
  • • And 9 more locations

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A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) - Join Clinical Trial NCTNCT06439082

How to Join This Clinical Trial - NCTNCT06439082

Learn how to participate in this PHASE3 trial studying an investigational therapy for Sickle Cell Disease. This study is currently enrolling participants.

Am I Eligible for This Clinical Trial?

This clinical research study is looking for participants with Sickle Cell Disease. Eligibility requirements include specific age ranges, health status, and medical history. Contact the study team to learn if you qualify.

Condition Being Studied
Sickle Cell Disease
Treatment Being Tested
Investigational treatment
Study Phase
PHASE3 - Large-scale efficacy study
Enrollment Status
Currently enrolling participants
Study Identifier
NCTNCT06439082 - ClinicalTrials.gov Identifier
Sponsored By
Study sponsor

What to Expect as a Participant

Participating in this clinical trial involves:

  • Initial screening to determine eligibility
  • Regular study visits and health assessments
  • Receiving the study treatment or placebo
  • Medical monitoring and follow-up care
  • Contributing to medical research that may help others
  • Potential access to new treatments before they're widely available

Clinical Trial Benefits and Compensation

Participants in this clinical research study may receive:

  • Close medical monitoring by healthcare professionals
  • Access to potential new treatments
  • Compensation for time and travel (varies by study)
  • No-cost study-related medical care
  • The opportunity to help advance medical knowledge

Where Is This Clinical Trial Located?

This study is enrolling participants at 12 locations. Find a study site near you:

Clinical Research Site

Washington D.C., District of Columbia 20010 - United States

Status: RECRUITING

Clinical Research Site

Jacksonville, Florida 32209 - United States

Status: RECRUITING

Clinical Research Site

Augusta, Georgia 30912 - United States

Status: RECRUITING

Clinical Research Site

Riverdale, Georgia 30274 - United States

Status: RECRUITING

Clinical Research Site

Louisville, Kentucky 40202 - United States

Status: RECRUITING

Clinical Research Site

The Bronx, New York 10467 - United States

Status: RECRUITING

Clinical Research Site

Greenville, North Carolina 27834 - United States

Status: RECRUITING

Clinical Research Site

Easton, Pennsylvania 18045 - United States

Status: RECRUITING

Clinical Research Site

Medellín, Antioquia 050001 - Colombia

Status: RECRUITING

Clinical Research Site

Santiago de Cali, Valle del Cauca Department 760012 - Colombia

Status: RECRUITING

And 2 more locations available. Contact us to find the nearest participating site.

How to Enroll in This Study

To learn more about participating in this PHASE3 clinical trial for Sickle Cell Disease:

  1. Review the eligibility criteria with your healthcare provider
  2. Contact the study team for a pre-screening interview
  3. Schedule an in-person screening visit if eligible
  4. Review and sign the informed consent form
  5. Begin participation in the clinical trial

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