Patient Guide: First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

We'll Help You Connect with This Trial

Quri.ai is a free clinical trial matching service. We help patients like you connect directly with research sites conducting this study.

  • ✓ Get matched to the right study location for you
  • ✓ Connect directly with study coordinators at 23 participating sites
  • ✓ Understand eligibility with our simplified screening tool
  • ✓ Free service - we're here to help you access clinical research
Trial ID: NCTNCT06043817
Status: 🟢 Enrolling Now
Condition: Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation
Phase: PHASE1, PHASE2

Find a Study Location Near You

This study is available at 23 research sites. We'll help you connect with the location that's right for you.

Participating sites include:
  • • Duarte, California
  • • Huntington Beach, California
  • • Irvine, California
  • • And 20 more locations - let us help you find the closest one

Loading interactive enrollment tools...

The full interactive experience will load momentarily

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations - Join Clinical Trial NCTNCT06043817

How to Join This Clinical Trial - NCTNCT06043817

Learn how to participate in this PHASE1, PHASE2 trial studying an investigational therapy for Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation. This study is currently enrolling participants.

Am I Eligible for This Clinical Trial?

This clinical research study is looking for participants with Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation. Eligibility requirements include specific age ranges, health status, and medical history. Contact the study team to learn if you qualify.

Condition Being Studied
Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation
Treatment Being Tested
Investigational treatment
Study Phase
PHASE1, PHASE2 - Safety and effectiveness study
Enrollment Status
Currently enrolling participants
Study Identifier
NCTNCT06043817 - ClinicalTrials.gov Identifier
Sponsored By
Study sponsor

What to Expect as a Participant

Participating in this clinical trial involves:

  • Initial screening to determine eligibility
  • Regular study visits and health assessments
  • Receiving the study treatment or placebo
  • Medical monitoring and follow-up care
  • Contributing to medical research that may help others
  • Potential access to new treatments before they're widely available

Clinical Trial Benefits and Compensation

Participants in this clinical research study may receive:

  • Close medical monitoring by healthcare professionals
  • Access to potential new treatments
  • Compensation for time and travel (varies by study)
  • No-cost study-related medical care
  • The opportunity to help advance medical knowledge

Where Is This Clinical Trial Located?

This study is enrolling participants at 23 locations. Find a study site near you:

Clinical Research Site

Duarte, California 91010 - United States

Status: RECRUITING

Clinical Research Site

Huntington Beach, California 92648 - United States

Status: RECRUITING

Clinical Research Site

Irvine, California 92618 - United States

Status: RECRUITING

Clinical Research Site

Charlotte, North Carolina 28204-2990 - United States

Status: RECRUITING

Clinical Research Site

Philadelphia, Pennsylvania 19107 - United States

Status: RECRUITING

Clinical Research Site

Nashville, Tennessee 37203 - United States

Status: RECRUITING

Clinical Research Site

Houston, Texas 77030-4009 - United States

Status: RECRUITING

Clinical Research Site

Salt Lake City, Utah 84112-5550 - United States

Status: RECRUITING

Clinical Research Site

Fairfax, Virginia 22031-2171 - United States

Status: RECRUITING

Clinical Research Site

Saint-Herblain, Loire-Atlantique 44115 - France

Status: RECRUITING

And 13 more locations available. Contact us to find the nearest participating site.

How to Enroll in This Study

To learn more about participating in this PHASE1, PHASE2 clinical trial for Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation:

  1. Review the eligibility criteria with your healthcare provider
  2. Contact the study team for a pre-screening interview
  3. Schedule an in-person screening visit if eligible
  4. Review and sign the informed consent form
  5. Begin participation in the clinical trial

Why Choose Quri.ai as Your Clinical Trial Matching Service

Quri.ai is a free clinical trial matching service that helps patients connect with research sites. We make it easier to:

  • Find clinical trials that match your condition
  • Get matched to the right study location near you
  • Connect directly with study coordinators
  • Understand if you qualify with simplified eligibility screening
  • Navigate the enrollment process with personalized support
  • Access new treatments through clinical research participation