Patient Guide: A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

We'll Help You Connect with This Trial

Quri.ai is a free clinical trial matching service. We help patients like you connect directly with research sites conducting this study.

  • ✓ Get matched to the right study location for you
  • ✓ Connect directly with study coordinators at 90 participating sites
  • ✓ Understand eligibility with our simplified screening tool
  • ✓ Free service - we're here to help you access clinical research
Trial ID: NCTNCT05031780
Status: ACTIVE_NOT_RECRUITING
Condition: Sickle Cell Disease
Phase: PHASE2, PHASE3

Find a Study Location Near You

This study is available at 90 research sites. We'll help you connect with the location that's right for you.

Participating sites include:
  • • La Jolla, California
  • • Los Angeles, California
  • • Oakland, California
  • • And 87 more locations - let us help you find the closest one

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A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP) - Join Clinical Trial NCTNCT05031780

How to Join This Clinical Trial - NCTNCT05031780

Learn how to participate in this PHASE2, PHASE3 trial studying an investigational therapy for Sickle Cell Disease. Current status: ACTIVE_NOT_RECRUITING.

Am I Eligible for This Clinical Trial?

This clinical research study is looking for participants with Sickle Cell Disease. Eligibility requirements include specific age ranges, health status, and medical history. Contact the study team to learn if you qualify.

Condition Being Studied
Sickle Cell Disease
Treatment Being Tested
Investigational treatment
Study Phase
PHASE2, PHASE3 - Large-scale efficacy study
Enrollment Status
ACTIVE_NOT_RECRUITING
Study Identifier
NCTNCT05031780 - ClinicalTrials.gov Identifier
Sponsored By
Study sponsor

What to Expect as a Participant

Participating in this clinical trial involves:

  • Initial screening to determine eligibility
  • Regular study visits and health assessments
  • Receiving the study treatment or placebo
  • Medical monitoring and follow-up care
  • Contributing to medical research that may help others
  • Potential access to new treatments before they're widely available

Clinical Trial Benefits and Compensation

Participants in this clinical research study may receive:

  • Close medical monitoring by healthcare professionals
  • Access to potential new treatments
  • Compensation for time and travel (varies by study)
  • No-cost study-related medical care
  • The opportunity to help advance medical knowledge

Where Is This Clinical Trial Located?

This study is enrolling participants at 90 locations. Find a study site near you:

Clinical Research Site

La Jolla, California 92037-1337 - United States

Status: Contact for availability

Clinical Research Site

Los Angeles, California 90095-1678 - United States

Status: Contact for availability

Clinical Research Site

Oakland, California 94609 - United States

Status: Contact for availability

Clinical Research Site

Farmington, Connecticut 06030-0001 - United States

Status: Contact for availability

Clinical Research Site

Washington D.C., District of Columbia 20010-2916 - United States

Status: Contact for availability

Clinical Research Site

Washington D.C., District of Columbia 20010 - United States

Status: Contact for availability

Clinical Research Site

Miami, Florida 33101 - United States

Status: Contact for availability

Clinical Research Site

Chicago, Illinois 60637-1443 - United States

Status: Contact for availability

Clinical Research Site

Indianapolis, Indiana 46202-5109 - United States

Status: Contact for availability

Clinical Research Site

Shreveport, Louisiana 71103-4228 - United States

Status: Contact for availability

And 80 more locations available. Contact us to find the nearest participating site.

How to Enroll in This Study

To learn more about participating in this PHASE2, PHASE3 clinical trial for Sickle Cell Disease:

  1. Review the eligibility criteria with your healthcare provider
  2. Contact the study team for a pre-screening interview
  3. Schedule an in-person screening visit if eligible
  4. Review and sign the informed consent form
  5. Begin participation in the clinical trial

Why Choose Quri.ai as Your Clinical Trial Matching Service

Quri.ai is a free clinical trial matching service that helps patients connect with research sites. We make it easier to:

  • Find clinical trials that match your condition
  • Get matched to the right study location near you
  • Connect directly with study coordinators
  • Understand if you qualify with simplified eligibility screening
  • Navigate the enrollment process with personalized support
  • Access new treatments through clinical research participation